What are some over-the-counter medications used for depression?

St. John's Wort and SAM-e are recognized as over-the-counter options for addressing symptoms of depression. St. John's Wort is an herbal remedy that has been studied for its effectiveness in mild to moderate depression and is thought to work by influencing neurotransmitters in the brain, similarly to conventional antidepressants. SAM-e, or S-adenosyl-L-methionine, is a compound that naturally occurs in the body and is involved in the production of neurotransmitters, potentially improving mood and alleviating depressive symptoms.

The other options do not align with established over-the-counter treatments for depression. While Advil and Tylenol are analgesics used for pain relief, they do not have effects on mood or depression. Ginseng and Omega-3 fatty acids may have some mood-stabilizing properties, but they are not primarily indicated for depression. Similarly, Vitamins C and D3 are important for overall health and have various benefits, but they are not specifically treatments for depression. Therefore, St. John's Wort and SAM-e represent more effective and recognized over-the-counter approaches for managing depressive symptoms.