What is a common consequence of tolerance developed from benzodiazepine use?

The correct choice, which indicates that a common consequence of developing tolerance from benzodiazepine use is the decreased effectiveness of the drug, highlights an essential aspect of pharmacology. Tolerance occurs when an individual becomes accustomed to a substance, leading to a diminished response to the drug after repeated use. In the case of benzodiazepines, this means that over time, the same dosage will result in less of the expected therapeutic effect, prompting individuals to increase their dosage to achieve the desired calming or anxiety-reducing effects. This increased need for dosage can result in a multitude of negative outcomes, including a higher risk of dependence and potential overdose.

Understanding tolerance is crucial when considering the long-term use of benzodiazepines for conditions like anxiety or sleep disturbances. It underscores why healthcare professionals aim to limit the duration of benzodiazepine prescriptions and encourage alternative therapies or medications that do not carry the same risk of tolerance.

Other choices do not align with the concept of tolerance in the same manner. For instance, increased appetite and enhanced memory recall do not directly relate to the common physiological response seen with prolonged benzodiazepine use. Heightened anxiety could stem from withdrawal or rebound effects when the drug is reduced or stopped, but it is not a direct