Which enzyme is Vilazodone a substrate of?

Vilazodone is primarily metabolized by the CYP3A4 enzyme, which is part of the cytochrome P450 enzyme system involved in drug metabolism. This enzyme plays a significant role in the oxidation of many pharmacological compounds, making it a key player in the biotransformation processes that affect the pharmacokinetics of various medications.

Understanding the role of CYP3A4 in the metabolism of Vilazodone is crucial for clinicians, as it can influence drug interactions, efficacy, and safety profiles for patients taking this medication. When drugs that either inhibit or induce CYP3A4 are co-administered, they can significantly affect the levels of Vilazodone in the body, potentially leading to therapeutic failure or increased side effects. This highlights the importance of considering enzymatic pathways in medication management and patient care.